Tested Species Reactivity:HumanProduct Format:Liquid. Supplied in 0.5%Bovine Serum Albumin (BSA), 0.1%Kathon CG/ICP, 10x Tris-Buffered Saline (TBS), Type 3 MilliQ H2O and 50% glycerol. Clonality:Monoclonal Clone:ABT-Arg1Isotype:IgGHost:MouseApplication:IHC-PAdditional Information:Retrieval buffer: TRIS-EDTA of pH8.0:::Description: Mouse monoclonal to Arginase-1Reconstitution and Storage:Shipped at 4C. Store at -20C. Stable for 12 months at -20C.Immunogen:The antiserum was produced against synthesized peptide derived between 280-322 aa of human ARG1. The exact sequence is proprietary.Purification:Immunogen affinity purifiedDatasheets/Manuals:Printable datasheet for OAAF08372Specificity:Anti-Arginase-1 [ABT-Arg1] detects endogenous levels of total Arginase-1 protein.Application Info:IHC 1:200 - 1:400 Gene Symbol:ARG1Official Gene Full Name:arginase 1Alias Symbols:Liver-type arginase, Type I arginaseNCBI Gene Id:383Protein Name:arginase-1Description of Target:Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.Swissprot Id:P05089Protein Accession #:NP_000036.2Nucleotide Accession #:NM_000045.3Molecular Weight:35 kDaTissue Tool:Find tissues and cell lines supported by DNA array analysis to express ARG1. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express ARG1. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。