Gene Symbol:BAXOfficial Gene Full Name:BCL2-associated X proteinNCBI Gene Id:581Swissprot Id:Q07812Protein Accession #:NP_001278357.1Nucleotide Accession #:NM_001291428.1Alias Symbols:BCL2L4Replacement Item:This antibody may replace item sc-20067 from Santa Cruz Biotechnology.Description of Target:The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.Molecular Weight:21 kDaHost:RabbitClonality:PolyclonalApplication:IFTissue Tool:Find tissues and cell lines supported by DNA array analysis to express BAX. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express BAX. Predicted Species Reactivity:Human, Mouse, RatPredicted Homology Based on Immunogen Sequence:Human, Mouse, RatProduct Format:LiquidReconstitution and Storage:Store at 2-8C for up to 6 months. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.Datasheets/Manuals:Printable datasheet for anti-BAX (OAAB20094) antibodyPreservative:0.02% Sodium Azide and 50% glycerolTarget Post-Translational Modification:Phospho-Thr167Formulation:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Isotype:Rabbit IgG 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。