Gene Symbol:CCR1Official Gene Full Name:chemokine (C-C motif) receptor 1NCBI Gene Id:1230Protein Name:C-C chemokine receptor type 1Swissprot Id:P32246Protein Accession #:NP_001286.1Nucleotide Accession #:NM_001295.2Alias Symbols:CKR1, CD191, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1Description of Target:This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.Protein Size (# AA):355Molecular Weight:39 kDaHost:RabbitClonality:PolyclonalPurification:Affinity purifiedApplication:WBTissue Tool:Find tissues and cell lines supported by DNA array analysis to express CTPS. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express CCR1. Immunogen:The immunogen is a synthetic peptide directed towards the middle region of human CCR1Predicted Species Reactivity:HumanTested Species Reactivity:HumanPeptide Sequence:Synthetic peptide located within the following region: KNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Concentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-CCR1 (ARP77951_P050) antibody is Catalog # AAP77951Datasheets/Manuals:Printable datasheet for anti-CCR1 (ARP77951_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。