Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Replacement Item:This antibody may replace item sc-393613 from Santa Cruz Biotechnology.Immunogen:The immunogen is a synthetic peptide directed towards the N-terminal region of Human DKFZp686M216Purification:Affinity PurifiedPredicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%Complete computational species homology data:Anti-ARNT2 (ARP33686_P050)Peptide Sequence:Synthetic peptide located within the following region: VTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-ARNT2 (ARP33686_P050) antibody is Catalog # AAP33686Datasheets/Manuals:Printable datasheet for anti-ARNT2 (ARP33686_P050) antibodySpecificity:This antibody is specific to both isoforms of hARNT2.Gene Symbol:ARNT2Official Gene Full Name:aryl-hydrocarbon receptor nuclear translocator 2Alias Symbols:bHLHe1, DKFZp686M216NCBI Gene Id:9915Protein Name:Putative uncharacterized protein DKFZp686M216 EMBL CAD97972.1Description of Target:This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.Swissprot Id:Q9HBZ2Protein Size (# AA):717Molecular Weight:79kDaTissue Tool:Find tissues and cell lines supported by DNA array analysis to express ARNT2. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express ARNT2. Protein Interactions:TRIM42; CEP57L1; RFX6; MIPOL1; DYDC1; SSX2IP; DTX2; SYCE1; RIMBP3; ZNF341; LZTS2; USHBP1; CEP63; CCDC33; NPAS3; RINT1; NDE1; ADAMTSL4; MTUS2; IKZF3; RBCK1; SPAG5; TACC3; CALCOCO2; SORBS3; PDE4DIP; TRAF4; BZRAP1; TFIP11; SSBP3; DGCR6; NCOA3; TRIP6; TRAF2; 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。