Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:IHC, WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Replacement Item:This antibody may replace item sc-116358 from Santa Cruz Biotechnology.Immunogen:The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28Purification:Affinity PurifiedPredicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%Complete computational species homology data:Anti-TRIM28 (ARP32677_P050)Peptide Sequence:Synthetic peptide located within the following region: PLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-TRIM28 (ARP32677_P050) antibody is Catalog # AAP32677 (Previous Catalog # AAPP03687)Datasheets/Manuals:Printable datasheet for anti-TRIM28 (ARP32677_P050) antibodySample Type Confirmation:TRIM28 is supported by BioGPS gene expression data to be expressed in HeLa
Target Reference:Kamitani,S., (2008) Biochem. Biophys. Res. Commun. 370 (2), 366-370 Gene Symbol:TRIM28Official Gene Full Name:Tripartite motif containing 28Alias Symbols:FLJ29029, KAP1, RNF96, TF1B, TIF1BNCBI Gene Id:10155Protein Name:Transcription intermediary factor 1-betaDescription of Target:TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING,a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.Swissprot Id:Q13263Protein Accession #:NP_005753Nucleotide Accession #:NM_005762Protein Size (# AA):835Molecular Weight:88kDaTissue Tool:Find tissues and cell lines supported by DNA array analysis to express TRIM28. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express TRIM28. Protein Interactions:WWOX; ERLIN2; HUWE1; SUMO1; UBC; SPRTN; SENP7; HAUS2; MAGEC2; CBX5; WHSC1; UBE2I; AURKA; SUMO2; SUMO3; RNF4; CEP250; TRIM28; HIF1A; CHD3; ATM; ZNF350; STAU1; HIST3H3; LYN; NEDD8; MDM2; ZBTB1; RPA3; RPA2; RPA1; RNF2; SUZ12; EZH2; BMI1; EED; BRCC3; WRNIP1; 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。