Tested Species Reactivity:HumanPredicted Species Reactivity:Mouse, Rat, Canine, Chicken, Cuttlefish, Equine, Guinea Pig, Porcine, Rabbit, Tree ShrewProduct Format:Liquid. Borate buffered saline, pH 8.2Clonality:PolyclonalHost:GoatConjugation:UNLB: UnconjugatedApplication:EM, ICC, IHC-F, IHC-P, WBAdditional Information:Description: Pooled antisera from goats hyperimmunized with type V collagen; purified by affinity chromatography on type V collagen covalently linked to agarose; reacts with conformational determinants on type V collagen; cross-adsorbed against Collagen types I, II, III, IV, and VI for minimal reactivityReconstitution and Storage:Store at 2-8CImmunogen:Type V collagenConcentration:0.4 mg/mLDatasheets/Manuals:Printable datasheet for OASB02745Specificity:Type V CollagenOfficial Gene Full Name:collagen type V alpha 1 chainTarget:COL5A1, COL5A2, COL5A3Alias Symbols:EDSC, EDSCL1NCBI Gene Id:1289; 1290; 50509Protein Name:collagen alpha-1(V) chainDescription of Target:This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants.Swissprot Id:P20908, P05997, P25940Protein Accession #:NP_000084.3Nucleotide Accession #:NM_000093.4Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express COL5A1. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express COL5A1. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
