Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Horse, Human, Pig, RabbitProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:EIF5BOfficial Gene Full Name:Eukaryotic translation initiation factor 5BNCBI Gene Id:9669Protein Name:Eukaryotic translation initiation factor 5BSwissprot Id:O60841Protein Accession #:NP_056988Nucleotide Accession #:NM_015904Alias Symbols:DKFZp434I036, FLJ10524, IF2, KIAA0741Replacement Item:This antibody may replace item sc-161555 from Santa Cruz Biotechnology.Description of Target:Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.Protein Size (# AA):1220Molecular Weight:139kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express EIF5B. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express EIF5B. Predicted Homology Based on Immunogen Sequence:Cow: 86%; Dog: 86%; Horse: 86%; Human: 100%; Pig: 93%; Rabbit: 93%Complete computational species homology data:Anti-EIF5B (ARP61644_P050)Peptide Sequence:Synthetic peptide located within the following region: SEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:TP53; TFCP2; UBC; LGR4; YBX3; ETS1; MMS19; FN1; CSNK2A1; PAXIP1; ECT2; BRCA1; EIF3C; CAND1; YWHAZ; SIRT7; HDGF; Mapk13; POU5F1; ZBTB3; PRKAA1; EIF1AX; CBL; gag;Blocking Peptide:For anti-EIF5B (ARP61644_P050) antibody is Catalog # AAP61644 (Previous Catalog # AAPP47743)Datasheets/Manuals:Printable datasheet for anti-EIF5B (ARP61644_P050) antibodySample Type Confirmation:EIF5B is strongly supported by BioGPS gene expression data to be expressed in Jurkat
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。