Tested Species Reactivity:HumanPredicted Species Reactivity:Human, MouseProduct Format:LyophilizedApplication:CAAdditional Information:Description: Twisted Gastrulation Protein (TSG) is a secreted BMP-binding protein that is structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP-4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP-4/Chordin complex.:::Bioactivity: Determined by its ability to neutralize BMP-6-induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is <= 2.0="" ug/ml="" of="">:::Endotoxin Level: Endotoxin level is <0.1 ng/ug="" of="" protein=""><1>Reconstitution and Storage:-20CPurity:98%Protein Sequence:CNKALCASDV SKCLIQELCQ CRPGEGNCSC CKECMLCLGA LWDECCDCVG MCNPRNYSDT PPTSKSTVEE LHEPIPSLFR ALTEGDTQLN WNIVSFPVAE ELSHHENLVS FLETVNQPHH QNVSVPSNNV HAPYSSDKEH MCTVVYFDDC MSIHQCKISC ESMGASKYRW FHNACCECIG PECIDYGSKT VKCMNCMFSource:E.coliTarget Reference:Tanno, T. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in Mouse and human cells. 2009. Blood; 114(1):181-6. Datasheets/Manuals:Printable datasheet for OPTA01113Alias Symbols:Twisted Gastrulation ProteinMolecular Weight:22.2 kDa 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
