Predicted Species Reactivity:Human, Mouse, RatProduct Format:Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Clonality:PolyclonalIsotype:IgGHost:RabbitApplication:WBReconstitution and Storage:Store at -20C. Avoid repeated freeze/thaw cycles.Replacement Item:This antibody may replace item sc-111047 from Santa Cruz Biotechnology.Immunogen:Synthesized peptide derived from human MLK3 around the phosphorylation site of S674. Location: 610-690aa.Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Concentration:1 mg/mlDatasheets/Manuals:Printable datasheet for anti-MAP3K11 (OASG04571) antibodyTarget Post-Translational Modification:Phospho-Ser674Specificity:Phospho-MLK3 (S674) Polyclonal Antibody detects endogenous levels of MLK3 protein only when phosphorylated at S674.Application Info:WB 1:500-1:2000; ELISA 1:5000;Gene Symbol:MAP3K11Official Gene Full Name:mitogen-activated protein kinase kinase kinase 11Alias Symbols:MAP3K11, MLK3, PTK1, SPRK, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinaseNCBI Gene Id:4296; 26403; 309168 Description of Target:The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.Swissprot Id:Q16584, Q80XI6, Q66HA1Molecular Weight:92 kDaTissue Tool:Find tissues and cell lines supported by DNA array analysis to express MAP3K11. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express MAP3K11. 
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
