Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:TFAP2BOfficial Gene Full Name:Transcription factor AP-2 beta (activating enhancer binding protein 2 beta)NCBI Gene Id:7021Protein Name:Transcription factor AP-2-betaSwissprot Id:Q92481Protein Accession #:NP_003212Nucleotide Accession #:NM_003221Alias Symbols:AP-2B, AP2-B, MGC21381Replacement Item:This antibody may replace item sc-113759 from Santa Cruz Biotechnology.Description of Target:TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes.This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-144 AU141084.1 1-144 145-1684 BC037225.1 1-1540 1685-5370 AL049693.16 11928-15613 5371-5770 BU738725.1 18-417 cProtein Size (# AA):460Molecular Weight:50kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express TFAP2B. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express TFAP2B. 
Immunogen:The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2BPredicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 82%; Zebrafish: 85%Complete computational species homology data:Anti-TFAP2B (ARP38283_P050)Peptide Sequence:Synthetic peptide located within the following region: ALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRKConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:YEATS4; UBC; KCTD1; UBE2I; SUMO1; SSBP4; LZTR1; VPS11; HIST1H2AC; CITED4; MYC; CITED2; CITED1;Blocking Peptide:For anti-TFAP2B (ARP38283_P050) antibody is Catalog # AAP38283 (Previous Catalog # AAPP23122)Datasheets/Manuals:Printable datasheet for anti-TFAP2B (ARP38283_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
