Tested Species Reactivity:Human, MousePredicted Species Reactivity:HumanProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:KCND3Official Gene Full Name:potassium voltage-gated channel subfamily D member 3NCBI Gene Id:3752Protein Name:potassium voltage-gated channel subfamily D member 3Swissprot Id:Q9UK17Protein Accession #:NP_004971.2Nucleotide Accession #:NM_004980.4Alias Symbols:KV4.3, SCA19, SCA22, BRGDA9, KCND3L, KCND3S, KSHIVBReplacement Item:This antibody may replace item sc-11686 from Santa Cruz Biotechnology.Description of Target:Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.Protein Size (# AA):655Molecular Weight:72 kDaPurification:Affinity purifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express KCND3. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express KCND3. 
Immunogen:The immunogen is a synthetic peptide directed towards the N terminal region of human KCND3Predicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%Complete computational species homology data:Anti-KCND3 (ARP36727_P050)Peptide Sequence:Synthetic peptide located within the following region: GLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:NDUFS2; NAP1L1; LBR; HSPA8; HSPA5; HNRNPF; XRCC6; EWSR1; EMD; DDB1; CUX1; CDK1; AUP1; NONO; XRCC5; UQCRC2; TUBB2A; RCN2; Rapgef5; Rapgef4; Kcnip1; Rapgef3; Kcnip2; DPP10; PYCR2; VPS4A; TUBA1B; G3BP1; RUVBL1; CNBP; SRC; KCND3;Blocking Peptide:For anti-KCND3 (ARP36727_P050) antibody is Catalog # AAP36727Datasheets/Manuals:Printable datasheet for anti-KCND3 (ARP36727_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
