Tested Species Reactivity:HumanPredicted Species Reactivity:HumanProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:BEST1Official Gene Full Name:bestrophin 1NCBI Gene Id:7439Protein Name:bestrophin-1Swissprot Id:O76090-4Protein Accession #:NP_001132915.1Nucleotide Accession #:NM_001139443.1Alias Symbols:ARB, BMD, BEST, RP50, VMD2, TU15BDescription of Target:This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.Protein Size (# AA):498Molecular Weight:57 kDaPurification:Affinity purifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express BEST1. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express BEST1. 
Immunogen:The immunogen is a synthetic peptide directed towards the middle region of human BEST1Peptide Sequence:Synthetic peptide located within the following region: KAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-BEST1 (ARP79553_P050) antibody is Catalog # AAP79553Datasheets/Manuals:Printable datasheet for anti-BEST1 (ARP79553_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
