Gene Symbol:CBFA2T3Official Gene Full Name:Core-binding factor, runt domain, alpha subunit 2; translocated to, 3NCBI Gene Id:863Protein Name:Protein CBFA2T3Swissprot Id:O75107Protein Accession #:BAA31276Nucleotide Accession #:NM_005187Alias Symbols:ETO2, MTG16, MTGR2, ZMYND4Replacement Item:This antibody may replace item sc-166058 from Santa Cruz Biotechnology.Description of Target:The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.Protein Size (# AA):545Molecular Weight:60kDaHost:RabbitClonality:PolyclonalPurification:Protein A purifiedApplication:WBTissue Tool:Find tissues and cell lines supported by DNA array analysis to express CBFA2T3. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express CBFA2T3. Immunogen:The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3Predicted Species Reactivity:HumanTested Species Reactivity:HumanPredicted Homology Based on Immunogen Sequence:Human: 100%Complete computational species homology data:Anti-CBFA2T3 (ARP38578_T100)Peptide Sequence:Synthetic peptide located within the following region: MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGPProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Concentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2;Blocking Peptide:For anti-CBFA2T3 (ARP38578_T100) antibody is Catalog # AAP38578 (Previous Catalog # AAPP20768)Datasheets/Manuals:Printable datasheet for anti-CBFA2T3 (ARP38578_T100) antibodySample Type Confirmation:CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。