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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
| CatalogNumber: 26382 |
| GeneSymbol: ERBB2/HER2/Neu/c-Neu |
| Description: Anti-ERBB2(D769Y)MouseMonoclonalAntibody |
| Background: TheHER-2/neuoncogene,amemberoftheepidermalgrowthfactorreceptororerb-Bgene-likefamily,encodesatransmembranetyrosinekinasereceptorthatmediatesextracellularsignalsactivatedbyepidermalgrowthfactors.Her2abnormalhasbeenstronglyassociatedwithmanymalignanttumors,especiallywithbreastcancers.TheexpressionlevelofHer2isanimportantcritiriainclinicevaluatingoftheprogressionofbreastcancer. |
| Immunogen: AsyntheticpeptidefromtheinternalregionofERBB2whichincludesthemutationofD769Y,humanorigin. |
| Applications: ELISA,IF,IHC |
| RecommendedDilutions: ELISA:1:1000-1:2000IF:1:500-1:1000IHC:1:50-1:100 |
| Concentration: 1mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purifiedfromascites |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: RecognizesD769Ymutant,butnotwild-typeERBB2ofvertebrates. |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet:  |
| Immunofluorescence: |
| ImmunofluorescenceofcellsexpressingERBB2proteinswithanti-ERBB2(D769Y)antibody.HEK293TcellsweretransfectedwithpCDNA3-GFP-ERBB2(D769Y)plasmid,pCDNA3-GFP-ERBB2(WT)plasmidorpCDNA3-GFP-ERBB2(D769H)plasmid,thenfixedandstainedwithanti-ERBB2(D769Y)monoclonalantibody(Cat.#26382). |
| RelatedProducts | |||||
| Catalog# | Name | Size | Price | DataSheet | |
| 21200 | Anti-ERBB2RabbitpolyclonalAntibody | 100μL | $219 |  | |
| 21202 | Anti-ERBB2RabbitPolyclonalAntibody | 100μL | $219 | | |
| 26127 | Anti-ERBB2mousemonoclonalAntibody | 100μL | $239 | | |
| 26080 | Anti-ERBB2(V777A)mousemonoclonalAntibody | 100μL | $495 | | |
| 26382 | Anti-ERBB2(D769Y)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26381 | Anti-ERBB2(D769H)MouseMonoclonalAntibody | 100μL | $495 | | |
