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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
| CatalogNumber: 26251 |
| GeneSymbol: FGFR1,BFGFR,CD331,CEK,FGFBR,FLG |
| Description: Anti-FGFR1(R78H)MouseMonoclonalAntibody |
| Background: TheproteinFGFR1ishighlyconservedbetweenmembersandthroughoutevolution.ThisparticularfamilymemberofFGFR1bindsbothacidicandbasicfibroblastgrowthfactorsandisinvolvedinlimbinduction.MutationsofFGFR1proteinhavebeenassociatedwithPfeiffersyndrome,Jackson-Weisssyndrome,Antley-Bixlersyndrome,osteoglophonicdysplasia,squamouscelllungcancerandautosomaldominantKallmannsyndrome. |
| Immunogen: AsyntheticpeptidefromtheinternalregionofFGFR1whichincludesthemutationofR78H,humanorigin. |
| Applications: ELISA,WB,IHC |
| RecommendedDilutions: ELISA:1:1000-1:2000WB:1:500-1:1000IHC:1:50-1:100 |
| Concentration: 0.5mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purifiedfromascites |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: RecognizesR78Hmutant,butnotwild-typeFGFR1ofvertebrates. |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet:  |
| Westernblot: |
| WesternblotanalysisofrecombinantFGFR1(R78H)andwildtypeproteins.PurifiedHis-taggedFGFR1(R78H)protein(aa22-376,~45KDa,lane2)andcorrespondingwildtypeprotein(lane1)wereblottedwithanti-FGFR1(R78H)monoclonalantibody(Cat.#26251). |
| Immunofluorescence: |
 | ImmunofluorescenceofcellsexpressingFGFR1proteinswithanti-FGFR1(R78H)antibody.HEK293TcellsweretransfectedwithpCDNA3-GFP-FGFR1(WT)plasmid(leftcolumn)orpCDNA3-GFP-FGFR1(R78H)plasmid(rightcolumn),thenfixedandstainedwithanti-FGFR1(R78H)monoclonalantibody(Cat.#26251). |
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| 26254 | Anti-FGFR1(P252S)MouseMonoclonalAntibody | 100μL | $495 | | |
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