品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
| CatalogNumber: 21276 |
| GeneSymbol: ATM |
| Description: Anti-ATMRabbitPolyclonalAntibody |
| Background: Ataxiatelangiectasiamutated(ATM)isaserine/threonineproteinkinasethatisrecruitedandactivatedbyDNAdouble-strandbreaks.ItphosphorylatesseveralkeyproteinsthatinitiateactivationoftheDNAdamagecheckpoint,leADIngtocellcyclearrest,DNArepairorapoptosis.ActivityofATMproteinisundertightcontrol,andmutationofATMcancausediseasesuchasAtaxiatelangiectasia(AT)andcancers. |
| Immunogen: PurifiedATMprotein,humanorigin. |
| Applications: ELISA,WB,IHC |
| RecommendedDilutions: ELISA:1:1000-1:5000WB:1:100-1:1000IHC:1:50-1:200 |
| Concentration: 0.2mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purifiedfromserum |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: RecognizesATMofvertebrates. |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet:  |
| Westernblot: |
| WesternblotanalysisofrecombinantATMprotein.PurifiedHis-taggedATMproteinwasblottedwithanti-ATMrabbitpolyclonalantibody(Cat.#21276). |
| Immunohistochemistry: |
 | Immunohistochemicalanalysisofparaffin-embeddedhumanthyroidcancertissuewithanti-ATMpolyclonalantibody(Cat.#21276).Tissuesampleswerefixedwithformaldehydeandblockedwith1%serumfor15minat37°C.Antigenretrievalwasbyheatmediationincitratebuffer(pH6).Sampleswerethenincubatedwithprimaryantibody(1:50dilution)overnightat4°C.AHRP-conjugatedGoatanti-mouseIgG(1:50dilution)wasusedassecondaryantibody. |
| RelatedProducts | |||||
| Catalog# | Name | Size | Price | DataSheet | |
| 21276 | Anti-ATMRabbitPolyclonalAntibody | 100μL | $219 |  | |
| 26141 | Anti-ATM(F858L)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26142 | Anti-ATM(Q2442P)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26140 | Anti-ATM(R3008H)MouseMonoclonalAntibody | 100μL | $495 | | |
| 26143 | Anti-ATM(R2443Q)MouseMonoclonalAntibody | 100μL | $495 | | |
