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DNA损伤修复在多种酶的作用下，生物细胞内的DNA分子受到损伤以后恢复结构的现象。DNA损伤修复的研究有助于了解基因突变的机制，衰老和癌变的原因，还可应用于环境致癌因子的检测。DNA修复可以引起抑癌基因的失活，原癌基因的激活，从而导致癌症的发生。人有超过130个基因与DNA的修复机制相关。
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Customer Reviews
BP1 Antibody (NB100-304)
Application: IHC
Sample Tested: Mouse thymocytes
Species: Mouse
Results: I needed to localize DSB repair at a single locus, so IHC was combined with DNA FISH. Many other antibodies failed because DNA FISH requires heating the cells to 80 degrees C which denatures most proteins. This anti-53BP1 antibody resulted in discrete, bright foci regardless of FISH hybridization.
FANCD2 Antibody (NB100-182)
Application: Western blot Sample Tested: PD20 cell line Species: Human
Ogg1 Antibody (NB100-106)
Application: IHC
Sample Tested: Human foreskin, adult ski, engineered human skin, keratinocytes, HaCaT cells
Species: Human
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