BDNF is a member of the nerve growth factor family of trophicfactors. In the brain, it has a trophic action on retinal,cholinergic and dopaminergic neurons. In the peripheral nervoussystem it acts on both motor and sensory neurons. Some proteindomains of BDNF are identical with those of NGF and anotherneurotrophic factor, designated NT-3. Polyclonal antibodiesraised against murine NGF have been shown to cross-react withboth NT-3 and BDNF. This carrier-free product is a recombinanthuman protein expressed in E. coli.
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