产品名称：AlbuVoid - Albumin Depletion Kit白蛋白去除试剂盒 英文名称：AlbuVoid - Albumin Depletion Kit 产品规格：10 Prep/50 Prep 产品货号：AVK-10/AVK-50 产品价格：3404.00/8153.00 产品产地：BSG

Albumin Depletion Plus Low Abundance Serum Protein Enrichment

● Albumin voids in flow-through 95%, with 30 minute bind/wash/elute protocol ● Low abundance enrichment equivalent or better than hexa-peptides or antibodies ● Disposable, cost-effective, no column regeneration or cross-contamination ● Mild elution maintains tertiary structure and simple transfer to secondary analysis ● The eluted fractions retain their enzymatic and biological activity ● Removes albumin from many species including human, sheep, bovine, goat, rat, and calf.

AlbuVoid , a silica-based protein enrichment matrix, removes albumin from serum and plasma samples while concentrating low abundance, and/or low molecular weight proteins. The AlbuVoid protocol uses mild buffers; the protocol conditions are so gentle that native enzyme activity is retained in elution fractions. AlbuVoid considerably enhances resolution of proteins below 50 kD, a limitation of alternate enrichment protocols.

AlbuVoid derives from a silica-based library of individual mixed-mode ligand combinations (ionic, hydrophobic, aromatic, polymer). The library was designed to facilitate weak binding of proteins, allowing for rapid elution from the matrix without any foreknowledge of the variety of proteins contained in the starting sample. In contrast to traditional chromatographic methods, our weak binding approach is more selective, presumably because of a lower degree of non-specific protein-protein interactions at the surface interface. In the case of AlbuVoid , a single, mixed-mode ligand architecture was selected empirically from the library. Because of its specific binding properties, AlbuVoid depletes high abundance proteins in serum like albumin and immunoglobulins while improving the resolution of less abundant serum proteins.

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