Alpha-Synuclein (α-Synuclein) is a 14 kD (140 amino acids) acidic presynaptic protein and is a major component of Parkinson’s Disease (PD) aggregates. α-Synuclein is implicated in the pathogenesis of PD and related neurodegenerative disorders. α-Synuclein also accumulates in the brains of sporadic PD patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of PD. α-Synuclein appears to associate with other proteins that aggregate and is found in beta-amyloid plaques and neuritic tangles in Alzheimer’s disease 3. rPeptide offers a wide array of synuclein products, including fragments, mutants, preformed fibrils, and labeled versions in addition to the wild-type protein. N15 uniformly labeled alpha-synuclein (α-synuclein) has all nitrogen’s N15 labeled.
用产品只提供给进一步的科研使用,不可应用于治疗等其他方面。 rPeptide是设在雅典,美国佐治亚州的一家生物技术公司,是一种在阿尔茨海默氏症和帕金森氏病的研究提供研究产品(重组多肽和蛋白质,抗体,试剂)市场的*。rPeptide还提供定制服务的范围从分子生物学,蛋白表达和纯化,13C和15N的多肽和蛋白质的统一标识。 rPeptide有一个专有的平台载体技术,使可溶性肽/蛋白在大肠杆菌中(如淀,β-淀粉样蛋白,瘦素,亲胰岛素)历史上的困难肽/蛋白表达。 商品名称 商品货号 商品品牌 Beta-Amyloid (1-40), Mouse, Rat A-1007-1 rPeptide Beta-Amyloid (1-40), Starter Kit A-1150-1 rPeptide Beta-Amyloid (1-40), Starter Kit A-1150-2 rPeptide Beta-Amyloid (1-40), Ultra Pure, HCl A-1156-1 rPeptide Beta-Amyloid (1-40), Ultra Pure, HCl A-1156-2 rPeptide Beta-Amyloid (1-40), Ultra Pure, HFIP A-1153-1 rPeptide Beta-Amyloid (1-40), Ultra Pure, HFIP A-1153-2 rPeptide Beta-Amyloid (1-40), Ultra Pure, NaOH A-1155-1 rPeptide Beta-Amyloid (1-40), Ultra Pure, NaOH A-1155-2 rPeptide Beta-Amyloid (1-40), Ultra Pure, TFA A-1001-1 rPeptide Beta-Amyloid (1-40), Ultra Pure, TFA A-1001-2 rPeptide Beta-Amyloid (1-40, D23N) A-1013-1 rPeptide Beta-Amyloid (1-40, D23N) A-1013-2 rPeptide Beta-Amyloid (1-40, F4W) A-1011-1 rPeptide Beta-Amyloid (1-40, F4W) A-1011-2 rPeptide