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Welcome to NetSci\'sList of Cheminformatics SoftwareIncludes Chemical DB, Reaction DB, Analysis, etc.Notice:Statements and opinions made for theproducts within this listing were supplied by their owners. NetworkScience Corporation assumes no responsibility for the content ofthese listings. All product and company names mentioned in thispublication are patents, trademarks, registered trademarks orservicemarks of their respective holders. The Tabular SoftwareListings portion of this site are Copyright ? 1995/2006 byNetwork Science Corporated. All rights reserved.The Software Section of NetSci is accessedby hundreds of scientists every week. Our goal is to make thisresource as comprehensive as possible. If your software program isnot included, please send e-mail with a brief description,the categories under which your program should appear, theplatforms supported, and contact information.For programs currently listed in NetSci,please check the table and description andnotify us of any changes oradditions. [A, B, C ] -- [D, E, F ] -- [G, H, I ] -- [J, K, L ][M, N, O ] -- [P, Q, R ] --[S, T, U ] --[V, W ] -- [X, Y, Z] --- A, B, C --- AutoNom (Automatic Nomenclature) is a chemical naming software system for Windows and Macintosh operating systems.It uses a proprietary algorithm based on IUPAC nomenclature rulesto generate IUPAC names automatically from chemical structures. The4.0 version of AutoNom adds the following new functionality:Chiral interpretation (R,S configurations) and double-bondtopology (E,Z descriptors)Support for CAS ring-system naming conventionsAbility to number atom locants within named structuresFor complete information, please consult http://www.beilstein.com CAMEO is a forward chaining reaction prediction program.Runs on VAX/VMS computer systems and uses Tektronix graphics.Contact:Prof. William L. JorgensenDepartment of ChemistryYale UniversityP. O. Box 208107New Haven, CT 06520-8107 USA.Tel: (203)432-6278Fax: (203)432-6299E-mail: bill@adrik.chem.yale.edu. The Catalyst environment wasdesigned for use by the practicing chemist and computational expertalike, stressing ease-of-use and a directed task-oriented approach.Catalyst unifies hypothesis generation, pharmacoporeidentification, and 3D database searching into a single environmentto accelerate the discovery of novel therapeutics. It is availablefrom Accelrys ChemExper is an online chemical database and searchingtool. This is a very powerful free search tool allowing, amongothers, a substructure search or physical/chemical characteristicssearch in the database of some 60000 chemicals. In near futurethere will be also IR spectra for 15000 chemicals available. Thecompany also offers a chemical bibliographical database (Experbib)and a user-friendly laboratory management program (Expereact).There is also an application allowing direct exportation of data tothe CCD. Additional information available atChemExper sprl36, clos de Profondval1490 Court-st-EtienneBelgiumhttp://www.chemexper.com/ ChemFileBrowser is free sotfware designed to visualize and work with SDF Files to exchange and analyse associated informations with chemical structures. It includes descriptors such as TPSA, molecular weight, HBd and Hba. ChemFinder Pro - Chemical searching and informationintegration. The first organizational software for today\'s chemist.Create electronic lab notebooks, find structure-activitycorrelations, calculate MW and much more. This chemistry-savvyorganizer greatly increases both your productivity and creativity.CS ChemFinder Pro acts as a gateway to chemical information sourcesand client-server with Beilstein, Oracle, Sybase and Rdb.ChemFinder is available from CambridgeSoft Chemkey The Chemkey Search computer database has beencompiled over a 30 year period and contains 45,000 referenceschosen from all the major organic journals. Particular attentionhas been devoted to synthetic methodology, asymmetric synthesis,heterocyclic chemistry, organometallic chemistry, stereochemistry,etc. Searching generally takes less than 30 seconds and the displayis instantaneous. Key references are provided which enable thechemist to rapidly peruse the literature for additional references.The database allows the user to conduct both wide or narrowsearching using wildcard and Boolean logic. Yearly updatescontaining 5,000 new references are added each year. Available forboth the Mac and IBM using Filemaker Pro technology with noadditional software required. For a demo sample of the databaseconnect to URL:http://euch6f.chem.emory.edu/. Available from:Heterodata Inc.1055 Rosewood DriveAtlanta, Ga. 30306Tel: (404)727-0283FAX: (404)727-6629E-mail: chemap@dooley.cc.emory.edu ChemProtect is a newsoftware program designed to help chemists in the selection ofprotective groups in synthesis. ChemTK Lite is a free, Windows-based toolkit providing chemists the ability to visualize, organize, query, and analyze chemical screening data. Features include: Visualization of SD files Organization of data by common scaffold Calculation of molecular descriptors Generation of predictive QSAR models Querying by substructure and/or property Generation of R tables Analysis of data by similarity and diversity Calculation of maximum common substructures (MCSs) Filtering and virtual screening of external filesAdditional information is available from Sage Informatics LLC. ChemTK evaluation software is available for download at http://www.chemtk.com. ChemTK is a Windows based cheminformatics toolkit providing chemists theability to visualize, organize, query, and analyze chemical screening data.It functions both as a simple and convenient SD file browser and as apowerful decision-support platform, offering intuitive clustering andproperty-calculation capabilities, QSAR model generation and virtualscreening, rapid similarity analyses, and many additional features. For a more thorough scientific discussion of ChemTK\'s features,see the following article in the most recent issue of JCICS (a link to the article is available from www.chemtk.com):Miller, D.W. A Chemical Class-Based Approach to PredictiveModel Generation. J. Chem. Inf. Comput. Sci. 2003, 43, 568-578. Chiron is an interactiveprogram for the analysis and perception of stereochemical featuresin molecules and for the selection of chiral precursors in organicsynthesis. emolecules is the world\'s leading free open-access chemistry search engine. emolecules\' mission is to discover, curate and index all of the public chemical information in the world, and make it available to the public. emolecules distinguishes itself by extremely fast searches, an appealing presentation of results, and high-quality chemical drawings. CIARA is a program that stores chemical information andassists in planning chemical reactions. It eliminates much of thetedious and time consuming work of calculating data such asmolecular weights, moles, reactant amounts, percent yields, etc. Aminimum amount of information is entered and CIARA does the rest.CIARA also is a database program so records can be stored andsearched. Each record in a CIARA database represents a singlechemical reaction. If you want to scale up a reaction simplyretrieve an existing record, change one value, and everything isrecalculated including solvent volumes. All this is done through aconvenient user friendly interface. CIARA is available fromVogel Scientific Software, Inc.1199 Leeward AveLake Elmo, MN 55042-9643Phone: 612-436-2998;FAX: 612-436-2798;E-mail: devogel@vogelscientific.comhttp://www.vogelscientific.com CLiDE, an acronym for Chemical Literature Data Extraction, is a documentimage processing software, which extracts content (i.e. structures, reactionsand text) of chemistry documents. While the major focus of CLiDE is toconvert scanned images of 2D structures into MOL or ChemDraw file formats, inthe latest version it can also convert 2D structures from PDF documents intovarious chemical file formats. CLiDE version 2.1 contains many new features and enhancements, including: handling of PDF input fileshandling of 4/8 bit bitmap input file formatsbetter superatom recognitionsimplified UIupdated help systemCLiDE v2.1 is available on various MS Windows platforms and it is offered intwo packages:the Lite version is focusing on structures only, and it is suitable foroccasional individual page or structure processingthe Full version extracts structures, text and reactions, and it is gearedtowards creating databases from the literature.For more information about CLiDE please visit our web site at http://www.simbiosys.ca or write us at clide@simbiosys.ca. The Lite version is also available from SciStore at http://chemstore.cambridgesoft.com/software/product.cfm?pid=269 Concord is used to quickly generate 3D structures from 2D or 2.5D connection tables. Concord is available from Tripos, Inc. CORINA is a 2D-to-3D conversion utility which is available on the WWW. --- D, E, F --- DARC (Description, Acquisition, Retrieval andCorrelation) is a chemical database system for storage, query andreporting on 2-D representations of chemical structures. Theprogram is generally available in Europe from: Questel83-85 Boulevard Vincent Auriol75646 Paris Cedex 13, FRANCETel: + 33 144 236464Fax: + 33 144 236465 Databases for cheminformatics research will be added to the databases.html file of the software lists. Check this listing regularly for new additions. DayMenus is a menu driven program which integrates alarge number of chemical information functions including structurespecification, display, lookup, cross referencing, searching,property prediction and data analysis. The software has been replaced with newer products and is no longer available. DEREK for Windows is a rule-based expert system that predicts the toxicological hazard of chemicals based on an analysis of their molecular structure. The software uses structure activity relationships (SAR or structural alerts) and gives some consideration to physicochemical properties to derive its predictions. All outcomes are peer reviewed by expert toxicologists and are supported by literature references. Alerts cover a wide range of toxicological end points, including carcinogenicity, mutagenicity, and skin sensitisation. All the tools are provided for users to add their own in-house alerts. DEREK for Windows is supported on NT and 2000. For further information contact: Nicole McSweeneyHead of SalesLhasa Limited22-23 Blenheim TerraceWoodhouse LaneLeeds LS2 9HDUnited Kingdomhttp://www.lhasalimited.orgTel. +44 (0) 113 3946061Fax +44 (0) 113 3946099Mobile +44 (0) 771 006 3808E-mail nicole.mcsweeney@lhasalimited.org DMax Chemistry Assistant? automatically finds, formulates, validatesand shows scientific hypotheses that best match small molecule screeningdata. Each discovered hypothesis suggests a relationship betweenmolecule structure and biological activity and thus contributes to theresearcher\'s insight in the underlying mechanism-of-action. In addition,the inferred hypotheses are combined into an auto-extracted expertsystem for in-silico screening and prioritization of large compoundlibraries. For each predicted score/rank, researchers can drill down topotential explanations and further down to the previously screenedreference molecules that back those explanations.DMax Chemistry Assistant can construct descriptive and predictive SARmodels referring to substructures of arbitrary complexity, not justpre-defined fingerprints.Kurt De GravePharmaDM nv.Kapeldreef 60, B-3001 Leuven, Belgiumphone: +32-16-298494URL: http://www.pharmadm.com/DMaxChemistryAssistant.asp DTREG (http://www.dtreg.com) generates SVM, decision tree and logistic regression models. Equbits Insight is a SVM based predictive modelingsoftware application designed for HTS and ADME chemists. Equbits Insight(tm)makes modeling easy and intuitive. You no longer need to be an expert inalgorithmic tuning or optimization to get the most accurate results. WithEqubits InsightT, you spend less time tuning and optimizing and spend moretime analyzing and interpretin. Equbits InsightT is designed with the userin mind, to deliver results. Predictive Modeling with Equbits InsightT is:Accurate- With Equbits Insight, users can generate the most accuratemodels and make better predictions Automated- Save users time and resources by automating modelgeneration Ease of Use- Unlike other tools, Equbits Insight can be used out ofthe box, bringing powerful accurate results Flexibile- Use Equbits Insight to provide modeling based on avariety of input descriptor types. With Equbits Insight, incorporate apriori knowledge to leverage existing knowledge to generate additionalaccuracyInterpretable- Equbits Insight provides users with easy to interpretresults. Integrate results with third party visualization tools for furtheranalysis Equbits Insight runs on Windows, Linux, and Solaris operatingsystems. To learn more, please contact:Ravi MallelaEqubits - Accelerating Drug DiscoveryPO Box 51977 Palo Alto, CA 94303Phone: 510-593-3223Fax: 650-855-9151Email: ravi@equbits.comWebsite: www.equbits.com EROS (Elaboration of Reactions for Organic Synthesis) isa computer assisted synthesis program developed by Gasteiger et.al.which uses a set of rules to propose synthetic routes. EROS isavailable from Dr. Johann Gasteiger, Erlangen University, Fulladdress is available at URLhttp://www2.chemie.uni-erlangen.de/ --- G, H, I --- ISIS (IntegratedScientific Information System) is aclient/server system providing comprehensive chemical informationmanagement. ISIS gives scientists a single interface to manage,communicate, and analyze a variety of scientific data storedthroughout a company\'s network.The ISIS family of products includes:ISIS/BaseISIS/DrawISIS/Host --- J, K, L --- JChem is a package that contains Java applicationsand software development tools for chemistry. The softwareis portable (runs under Windows, Mac OS X, Unix, etc.) JChem Base provides chemical database searching capabilities by integration into relational database engines supporting SQL.Modules include:Standardizer (new): Structure canonization tool converting molecules from different formats into standard representation.Screen (new): Screening based on pharmacophore or chemical fingerprints or other descriptors.Reactor (new): Generating reaction products from reaction equations and reactants.Fragmenter (new): Generating building blocks based on Recap rules from molecule libraries.Metabolizer (new): Metabolism simulation using user-defined transformation rules.JKlustor: clustering and diversity calculations based on molecular fingerprints or other properties.The software can be tried/downloaded at http://www.chemaxon.com/products.html. Online demos located at http://www.jchem.com/examples.html LHASA (Logic and Heuristics Applied to SyntheticAnalysis) is a sophisticated retrosynthetic analysis program whichcan be used to suggest novel synthetic routes. The program uses aknowledge base of transformations to describe generic chemicalreactions. The anaylsis of the compounds can be directed by the useof user-definable strategies and tactics. The program can alsosuggest an appropriate strategy based on its perception of themolecule. LHASA is now supported on VAX and most Unixplatforms. For futher information contact:Nicole McSweeneyHead of SalesLhasa Limited22-23 Blenheim TerraceWoodhouse LaneLeeds LS2 9HDUnited Kingdomhttp://www.lhasalimited.orgTel. +44 (0) 113 3946061Fax +44 (0) 113 3946099Mobile +44 (0) 771 006 3808E-mail nicole.mcsweeney@lhasalimited.org LiqCryst a database ofLiquid Crystalline Compounds for Personal Computers LOGKOW, a program developed at Syracuse Research Corporation is now free from the U.S. EPA website at http://www.epa.gov/oppt/exposure/docs/episuitedl.htm along with a number of other programs for MP, BP, VP, Henry\'s Law constant and a number of environmental fate processes (biodegradation, atmospheric oxidation, hydrolysis, etc.).LOGKOW is one of the more accurate fragment constant programs (e.g., see Tetko et al., J. Chem. Inf. Comput. Sci., 41: 1407-1421, 2001; W.M. Meylan and P.H. Howard. Atom/Fragment contribution method for estimating octanol-water partition coefficients. J. Pharm. Sci., 84: 83-92, 1995). --- M, N, O --- MACCS-II (MolecularACCess System. Has been replaced by the ISIS system). A mainframe application used to build, maintain, and search a company\'s proprietary and commercial databases of 2D and 3D chemicalstructures and associated research data stored in relationaldatabases.MDL offers a range of databases thattogether form an electronic library, giving chemistsstructure-searchable access to data selectively abstracted fromover 400 chemistry journals, 250 chemical supplier catalogs,pharmaceutical patent reports, company reports, regulatory reports,and conference proceedings. The databases -- updated annually,semiannually, or monthly -- cover synthetic methodology, metabolictransformations, 3D structures and data, available chemicals, andbioactivity information.The OHS Safety Seriesprovides the most comprehensive, independently researched chemicalhandling and safety information available. The suite of productsand services help organizations manage and make accessible materialsafety data on over 100,000 chemical products selected from theinventories of leading companies. Data is available on CD-ROM fordesktop computers or can be distributed in a client/server ormainframe environment. MDL also offers services to write materialsafety data sheets (MSDSs) for proprietary and for-sale chemicalsubstances. Contact MDL InformationSystems for additional information. Marvin Applets and Marvin Beans 3.0 have been released. The packagescontain software development tools and applications for chemistry. Marvin Applets and JavaBeans support drawing/displaying chemical structures and handling molecule objects.The following are freely available:Marvin Applets are free for free web sites. MarvinSketch and MarvinView applications accessed from ChemAxon\'s web site Locally installed MarvinSketch, MarvinView, and MolConverter applications. Important changes:Abbreviated groups, S-groups.3D cleaning, 3D conversion from 2D or SMILESElemental Analysis calculationsTools menu and plugins: Charge distribution, pKa, logP, logD.(Without license key only 1 calculation at a time is allowed)Creating user defined templates by dragging-and-dropping overtemplate buttons.Nicer looking molecules; atom properties are displayedseparately from element symbols.Radicals are supported.Faster import of large XYZ and PDB files.Molecule-related classes are 20-30% faster, R-group andreaction related classes are easier to use.Signed applet is the default (allowing clipboardoperations and the accessing of the local file system)The software can be tried/downloaded at http://www.chemaxon.com/products.html. Online access also is available for Applets and Applications. Merlin provides the ability to perform extremely fastsearches on selected data in Thor chemical information databases.Merlin operates on sets of structures and is ideal for exploratorydata analysis. Merlin is available from Daylight Chemical Information Systems METEOR originally resulted from a three year research project to develop a computer system for the intelligent prediction of the metabolic fate of xenobiotic chemicals. The software is continually developed alongside experts from various industry and academic sectors, with knowledge of biotransformations covering phase I and phase II metabolism. The software predicts the metabolic fate of a parent compound, and it also evaluates the likelihood that each predicted metabolite could be found in vivo. This evaluation considers physicochemical parameters, such as logP. Metabolites can be restricted to those most likely to be of interest by user defined controls. These include: Selection of confidence levels for metabolite generation Sequence termination at excretable metabolites.External link to ClogP The potential to make species specific predictions Restriction to either Phase I or Phase II processes The report for a query compound contains specific literature references, and links to external commercial metabolism databases are available. METEOR can also perform alongside DEREK for Windows, allowing a fast assessment of the likelihood of potential metabolites being toxic. For further information contact: Nicole McSweeneyHead of SalesLhasa Limited22-23 Blenheim TerraceWoodhouse LaneLeeds LS2 9HDUnited Kingdomhttp://www.lhasalimited.orgTel. +44 (0) 113 3946061Fax +44 (0) 113 3946099Mobile +44 (0) 771 006 3808E-mail nicole.mcsweeney@lhasalimited.org OPTIMA integrates informatics. Functioning within aclient/server operating environment, OPTIMA from EMAX is developedusing leading software and development tools. OPTIMA inter-connectsthe many disparate sources of information about every availablesubstance and reagent. Robotics and automated compound warehousesmay also be integrated to provide the complete solution.Functioning within a client/server operating environment, OPTIMAoffers a cradle to grave chemicals information solution thatincreases research productivity, safety and regulatory compliance.This research enterprise solution integrates technology with policyand process considerations to ensure successful deployment. OPTIMAis available fromEMAX Solution Partners, Inc.18 Campus Blvd.Newtown Square, PA 19073Tel: 610-325-3700 (800-551-EMAX)E-mail: moreinfo@emax.comhttp://www.sciquest.com/ --- P, Q, R --- Project Library: A complete, ready-to-use desktop software application for managing project-level combinatorialchemistry data. The system offers user-friendly tools that helpresearchers create and manage libraries of generic and specificstructures, along with associated bioassay, physical, andadministrative data. Project Library expedites planning by offeringa way to generate virtual libraries and, in conjunction with ISISand MDL\'s databases, manages each step of the combinatorialchemistry workflow -- from synthesis planning, through librarybuilding and compound screening, to data analysis. REACCS (ReactionACCess System). A mainframeapplication used to build, maintain, and search a company\'sproprietary and commercial databases of chemical reactions andrelated data. The product has been replaced and is no longer available.MDL offers a range of databases that together form an electroniclibrary, giving chemists structure-searchable access to dataselectively abstracted from over 400 chemistry journals, 250chemical supplier catalogs, pharmaceutical patent reports, companyreports, regulatory reports, and conference proceedings. Thedatabases -- updated annually, semiannually, or monthly -- coversynthetic methodology, metabolic transformations, 3D structures anddata, available chemicals, and bioactivity information. RS3 Discovery is a research informationsystems which supports structures, properties, and other data inORACLE 7 databases. The program is available from Accelrys --- S, T, U --- SciMetrics offers chemical prediction models for Vapor Pressure, Henry\'s Law, LogP, Water Solubility as well as the toxicity of chemicals to Tetrahymena Pyriformis and Fathead Minnow. The program SciPredict is free but the models (after a 10 day trial period) are priced at $150 each. The program models are based on the training of a Bayesian Regularized Neural Network. Preditions can be made individually by inputting SMILES strings or by processing files of SMILES strings or SD files. Additional information available from: Dr Frank BurdenSciMetrics23 Harrow StreetBlackburn SouthVIC 3130 AustraliaFax VoiceMail: 613 8611 7960frank.burden@scimetrics.com MDL SCREEN: An ORACLE-based, client/server datamanagement system for managing HTS information. Designed in workingHTS laboratories and developed with input from leading HTSscientists around the world, MDL SCREEN supports every stage of theHTS process, from experimental design and protocol management todata validation and decision control. Modular and scalable indesign, MDL SCREEN is an appropriate solution for any HTSoperation, from multinational life science enterprises to start-upbiotechnology firms. The software has been replaced and is no longer available. SECS (Simulation and Evaluation of Chemical Synthesis) isa retro-synthesis analysis program in much the same mold as LHASAand SYNCHEM. The target molecule is analyzed according to strategicreactions using a database of known reactions as a guide forpredicting single step transformations to simplified compounds.Several iterations of the procedure are required to develop asynthesis plan. Contact: W. Todd WipkeDepartment of ChemistryUniversity of CaliforniaSanta Cruz, CA 95064Tel: +1-408-459-2397Fax: +1-408-459-2935E-mail: wipke@chemistry.ucsc.edu SMILES Toolkit A programming library which provides basicfunctions needed for chemical information processing. The Toolkitis the basis for all other Daylight Toolkits. It is available from Daylight ChemicalInformation Systems SMOG The Structural MOlecularGeneration program exhaustively and non-redundantlygenerates chemical structures for a given molecular formula. Theprogram makes use of the graph-theoretical Faradjev algorithm. Itis written in C/C++ and runs on IBM PC compatible computers withEGA/VGA cards. The program occupies 1 Mb space and requires 2-3 Mbfree space for structure storage. It is available from the CCLarchives via ftp at ftp://ccl.osc.edu/pub/chemistry/software/MS-DOS/SMOG SYBYL/3DB UNITY is Tripos\' 3D-database and chemicalinformation system. Contact Tripos, Inc. SYNLIB (SYNthesis LIBrary) is a chemical reactionretrieval computer program through which laboratory scientists canrapidly search databases of chemical reaction information. A facilesketchpad method is available for building chemical structurediagrams. The searching portion of the program provides uniquemethods for querying chemical reaction libraries for matches tocombinations of both structural and non-structural chemicalquestions. SYNLIB runs on Silicon Graphics, HP9000/720, NECEWS4800, VAX/VMS and Macintosh II computer systems. Contact:W. Clark StillDepartment of ChemistryColumbia UniversityNew York, NY 10027 USA Tel: +1-212-280-2577Fax: +1-212-678-9039 Thor A high performance, full distributed database systemdesigned for the storage and retrieval of chemical information.Data fields have the capability of holding any amount or kind ofdata. Contact Daylight ChemicalInformation Systems TRIAD (TRIcyclics for Automated Design) is a database ofmore than 400,000 energy minimized molecular structuresrepresenting a comprehensive collection of tricyclic hydrocarbons.The database is available in MacroModel format (TRIAD-M) and CAVEATvector format (TRIAD-V). Contact:Office of Technology Licensing2150 Shattuck Avenue, STE 510Berkeley, CA 94704 USATel: +1-510-643-7201Fax: +1-510-642-4566E-mail: domino@garnet.berkeley.edu (e-mail) UVSS, from Genomining, lets you manage your virtual screening pipelines through an advanced batch scheduler. UVSS currently supports Gold, FlexX and Surflex. --- V, W --- Vcharge calculates accurate, conformation-independent, \"ab initio-like\" partial atomic charges for an SDfile of drug-like compounds in ~0.1 per compound. It is useful for a wide range of modeling and QSAR applications, and is available for Windows and Linux. Vcharge is an electronegativity equalization method in which the electronegativity of each atom depends upon its atomic number, hybridization, and bonding environment within the molecule. Electronegativities and hardnesses are averaged over alternate resonance forms of the molecule, which are automatically detected. The VC/2004 parameterization of Vcharge yields charges that accurately reproduce Hartree-Fock 6-31G* potentials at CHELPG sampling points, and that are strikingly similar to those in widely used force fields, such as AMBER and CHARMM22. The method is described in the following paper: Fast assignment of accurate partial atomic charges. An electronegativity equalization method that accounts for alternate resonance forms; Gilson,M.K., Gilson,H.S.R. Potter,M.J.; J. Chem. Inf. Comput. Sci. 2003, 43(6), 1982-1997. More information is available at http://www.verachem.com/Vcharge, and the program can be tried on-line at http://www.verachem.com/Vcharge2.html --- X, Y, Z --- NetSci, ISSN 1092-7360, is published by Network Science Corporation. Except where expressly stated, content at this site is copyright (? 1995 - 2010) by Network Science Corporation and is for your personal use only. No redistribution is allowed without written permission from Network Science Corporation. This web site is managed by:Network Science Corporation4411 Connecticut Avenue NW, STE 514Washington, DC 20008 Tel: (828) 817-9811 E-mail: TheEditors@netsci.orgWebsite Hosted by Total Choice
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