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BBI Solutions/Beta-2 Microglobulin (B2M)//P122-1
Beta 2 Microglobulin is a protein of 12kDa and pI of 5.6. B2M levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyspraxia, solid tumors and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
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