Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mL
Concentration: Purified: 1 mg/mL; TC Supernatant: Lot Specific
Clonality: Monoclonal
Form: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")
Host Species: Mouse
Immunogen: Fusion protein amino acids 208-427 (C-terminus) of mouse Arl13b (also known as ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL2-like protein 1 and Arl2l1, accession number Q640N2)Rat: 85% identity (189/220 amino acids identical)Human: 68% identity (154/224 amino acids identical)<40% identity with Arl13a
Target Description: ADP-ribosylation factor-like protein 13B (ARL13B), also known as ADP-ribosylation factor-like protein 2-like 1. Arl13B is a small GTPase with both N-terminal and C-terminal guanine nucleotide-binding motifs. Arl13B is localized to the membrane of cilia and expressed in Neuroepithelial cells and developing radial glia of the developing cerebral cortex. Mutations in this gene are the cause of Joubert syndrome 8.
Gene ID: Arl13b Arl2l1
Antibody Registry ID (RRID): AB_11001586
Physical State: Liquid
Validation and Application Notes
Molecular Weight: 50 kDa
NOTE
Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.
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鸡的概念 在一次会议上,他与同事的一次谈话说服了西蒙博士再次尝试制造这种抗体,但是尝试把鸡作为宿主——鸡在进化上与包括人类在内的哺乳动物完全不同。结果表明:人蛋白抗原具有高度的免疫原性,抗体产量异常高,免疫试剂结合紧密,特异性高。 今天的Aves 从那时起,Aves Labs开创了在蛋白质中寻找高免疫原性肽序列的新算法,开发了针对鸡抗体的新的亲和纯化方法,并开发了许多其他有用的试剂,如BlokHen®阻断试剂和PrecipHen®免疫沉淀试剂。Aves实验室继续开发针对神经特异性抗原和表位标签的新型抗体试剂,以促进神经科学和分子生物学领域的科学进步。