Description

TheXTTCellProliferationAssay(XTT-CPA)isasensitivekitforthemeasurementofcellproliferation.Cleavageofthetetrazoliumsalttoformazanoccursviathesuccinate-tetrazoliumreductasesysteminthemitochondriaofmetabolicallyactivecells.

Features:

• Allowsmeasurementofcellproliferation,cellviABIlityorcytotoxicity.
• Rapiddeterminationinmicroplates(nosolubilizationstepasinanMTTassay).
• ReproducIBLeandsensitiveresults.
• NorADIoactivity.
• Idealforhighthroughputassays(nowashingorotherstepsthatcancausecelllossandvariability).

Catalog#4891-025-Kincludes:
CatalogNumber	Description	Qty
4891-025-01	XTTReagent	1
4891-025-02	XTTActivator	1

 

Akt-ActivatedEndotheliumConstitutestheNicheforResidualDiseaseandResistancetoBevacizumabinOvarianCancer
BellaS.Guerrouahen,JenniferPasquier,NadineAbuKaoud,MahtabMaleki,Marie-ClaudeBeauchamp,AmberYasmeen,PegahGhiabi,RaphaelLis,FabienVidal,AhmedSaleh,WalterH.Gotlieb,ShahinRafii,andArashRafii
Mol.CancerTher.,Dec2014;13:3123–3136.
http://mct.aacrjournals.org/cgi/content/abstract/13/12/3123

ASpliceVariantoftheHumanIonChannelTRPM2ModulatesNeuroblastomaTumorGrowththroughHypoxia-inducibleFactor(HIF)-1/2{alpha}
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J.Biol.Chem.,Dec2014;289:36284–36302.
http://www.jbc.org/cgi/content/abstract/289/52/36284

“DepletionoftheHumanIonChannelTRPM2inNeuroblastoma
DemonstratesItsKeyRoleinCellSurvivalthroughModulationof
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“LeiBao,Shu-jenChen,KathleenConrad,KerryKeefer,ThomasAbraham,JohnP.Lee,JuFangWang,Xue-QianZhang,IwonaHirschler-Laszkiewicz,Hong-GangWang,SinisaDovat,BrianGans,MuniswamyMadesh,JosephY.Cheung,andBarbaraA.Miller”
J.Biol.Chem.,Nov2016;291:24449–24464
http://www.jbc.org/cgi/content/abstract/291/47/24449

Trevigen公司位于美国马里兰州的高科技走廊，是一家有12年历史、成长迅速的生物技术公司，其产品和技术的发展方向主要在癌症研究领域，重点强调细胞凋亡、DNA损伤和修复，以及癌症细胞功能和行为。Trevigen品牌的分销商遍及北美，欧洲和环太平洋地区。关于DNA的损伤分析技术的研究，Trevigen获得美国国立卫生研究院（NIH）的SBIR项目资助。