

Description | WAY-316606,aspecificantagoNISTofSFRP1,functionsasanactivatorofcanonicalWnt/β-cateninsignallinginthehumanhairbulb. | |
---|---|---|
Targets |
| |
Invitro | WAY-316606enhanceshairshaftproduction,hairshaftkeratinexpression,andinhibitsspontaneousHFregression(catagen)exvivo.WAY-316606effectivelyenhancesβ-cateninactivityinmammalianskincellpopulations,namelyinbothhumanhairpre-cortexkeratinocytesandDPfibroblastsexvivo[1]. |