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商品描述
Specifications
SPECIESREACTIVITY: | Gibbon,Gorilla,Human |
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TESTEDAPPLICATIONS: | IHC |
APPLICATIONS: | AADATantibodycanbeusedinWesternBlotstartingat0.5-2μg/mL,immunohistochemistrystartingat10μg/mL,andimmunoprecipitation. |
USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
SPECIFICITY: | BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins. |
IMMUNOGEN: | AADATantibodywasraisedagainstapeptidelocatedintheN-TerminalregionofAADAT(Human). |
HOSTSPECIES: | Rabbit |
Properties
PURIFICATION: | ImmunoaffinityChromatography |
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PHYSICALSTATE: | Liquid |
BUFFER: | PBS,0.1%sodiumazide. |
STORAGECONDITIONS: | StoreAADATantibodyat4˚Cforshorttermapplications.Forlongtermstorage,aliquotand-20˚C. |
CLONALITY: | Polyclonal |
CONJUGATE: | Unconjugated |
AdditionalInfo
ALTERNATENAMES: | AADAT,2-aminoADIpatetransaminase,KAT2,KAT/AadAT,KATII,KynurenineaminotransferaseII,Aminoadipateaminotransferase |
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ACCESSIONNO.: | Q8N5Z0 |
PROTEINGINO.: | 46395904 |
OFFICIALSYMBOL: | AADAT |
GENEID: | 51166 |
Background
BACKGROUND: | KynurenineaminotransferasecatalyzestheirreversIBLetransaminationoftheL-tryptophanmetaboliteL-kynureninetoformkynurenicacid.KynurenicacidisanantagoNISTattheglycinesiteofNMDAreceptorsandincreasedlevelsofkynurenicacidarethoughttoexertaneuroprotectiveactioninsomepathologicalconditions. |
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