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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Specifications
SPECIES: | Human |
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SOURCESPECIES: | E.coli |
SEQUENCE: | MRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY |
BIOLOGICALACTIVITY: | DeterminedbyitsABIlitytochemoattracthumanmonocytesusingaconcentrationrangeof10.0-10.0ng/mL. |
Properties
PURITY: | Greaterthan98%bySDS-PAGEgelandHPLCanalyses. Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
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PHYSICALSTATE: | Lyophilized |
STORAGECONDITIONS: | ThelyophilizedApo-SAA1recombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedApo-SAA1isstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingApo-SAA1recombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
AdditionalInfo
ALTERNATENAMES: | SAA,PIG4,SAA2,TP53I4,SerumamyloidA-1protein,AmyloidfibrilproteinAA,SAA |
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ACCESSIONNO.: | NP_000322.2 |
PROTEINGINO.: | 40316912 |
Background
SerumamyloidAproteins(SAA)representsafamilyofapolipoproteinsthatcirculatesinassociationwithhigh-densitylipoproteins(HDL).Thelevelofapo-SAA,normally1-5μg/mLinplasma,increases500-1000foldwithin24hoursofaninflammatorystimulusand,undertheseconditions,isthemostabundantHDLapo-lipoprotein.ThehumanSAAgenecodesfora122aminoacidnonglycosylatedpolypeptide,whichcontainsan18aminoacidN-terminalsequence.Recombinanthumanapo-SAA1isan11.7kDaproteincontaining105aminoacidresidues. |