Antigen/Purification: Collapse
The antigen is a human cell homogenate.
The antibody is Protein A purified.
Biological Significance: Collapse
Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.
Storage
100 µl liquid.
For long term storage –20° C is recommended in undiluted aliquots. Stable at –20° C for up to one year after date of receipt. Avoid freeze/thaw cycles.
General References
McBride HM, Neuspiel M, Wasiak S (2006) Mitochondria: More than just a powerhouse. Curr Biol. 16(14):R551-60
Green DR (1998) Apoptotic pathways: the roads to ruin. Cell 94(6):695-8.
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