Product ID D8276Cas No. 164656-23-9Purity ≥99%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

Dutasteride is an inhibitor of 5-α-reductase (types 1/2) that is clinically used to treat benign prostatic hyperplasia (BPH), often co-administered with tamsulosin. Dutasteride exhibits anti-inflammatory and anticancer chemotherapeutic activities. In prostatic cells, dutasteride induces apoptosis and inhibits cell proliferation. In vivo, this compound decreases prostate volume. In animal models, dutasteride suppresses growth of prostate tumors.

Product Info

Cas No.PurityFormulaFormula Wt.SynonymAppearance

164656-23-9

≥99%

C27H30F6N2O2

528.53

Avodart

White to off white powder

Shipping and Storage

Store TempShip Temp

-20°C

Ambient

Downloads

Info Sheet

D8276 Info Sheet PDF

References

Tsujimura A, Fukuhara S, Soda T, et al. Histologic evaluation of human benign prostatic hyperplasia treated by dutasteride: a study by xenograft model with improved severe combined immunodeficient mice. Urology. 2015 Jan;85(1):274.e1-8. PMID: 25444635.

Barkin J. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability. Patient Prefer Adherence. 2011;5:483-90. PMID: 22003286.

Arena F. Dutasteride in the treatment of hormone refractory prostate cancer. Minerva Urol Nefrol. 2008 Jun;60(2):71-6. PMID: 18500220.

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