MedKoo Cat#: 510262A Name: Phosphatidyl choline (from Soybean) CAS#: 8002-43-5 (from Soybean) Chemical Formula: N/A (mixture) Exact Mass: 0.0 Molecular Weight: 0.0 Elemental Analysis: N/A (mixture)
Synonym: 1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC. Phosphatidyl choline.
IUPAC/Chemical Name: (Z)-3-(oleoyloxy)-2-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate.
InChi Key: RRVPPYNAZJRZFR-MRCUWXFGSA-N
InChi Code: InChI=1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-
SMILES Code: O=P(OCC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=CCCCCCCCC)=O)([O-])OCC[N+](C)(C)C
Technical Data
Appearance: Yellow to light brown semi-solid or wax solid.
Purity: >98% (or refer to the Certificate of Analysis)
Certificate of Analysis: View CoA: current batch, Lot#BBC40306
Safety Data Sheet (MSDS): View Material Safety Data Sheet (MSDS)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code: 293490
Additional Information
Related CAS# 8002-43-5 ( Phosphatidyl cholinefrom Soybean); 8057-53-2 ( Phosphatidyl choline from egg yolk)
Phosphatidylcholine is a major constituent of cell membranes and pulmonary surfactant, and is more commonly found in the exoplasmic or outer leaflet of a cell membrane. It is thought to be transported between membranes within the cell by phosphatidylcholine transfer protein (PCTP). Phosphatidylcholine also plays a role in membrane-mediated cell signaling and PCTP activation of other enzymes. The phospholipid is composed of a choline head group and glycerophosphoric acid, with a variety of fatty acids, one being a saturated fatty acid (in the given figure, this can be palmitic or hexadecanoic acid, H3C-(CH2)14-COOH; margaric acid identified by Gobley in egg yolk, or heptadecanoic acid H3C-(CH2)15-COOH, also belong to that class); and one being an unsaturated fatty acid (here oleic acid, or 9Z-octadecenoic acid, as in Gobley\'s original egg yolk lecithin). Phospholipase D catalyzes the hydrolysis of phosphatidylcholine to form phosphatidic acid (PA), releasing the soluble choline headgroup into the cytosol. Phosphatidylcholine is a neutral lipid, but it carries an electric dipole moment of about 10 D. (http://en.wikipedia.org/wiki/Phosphatidylcholine)
References
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