MedKoo Cat#: 100300 Name: Erlotinib hydrochloride CAS#: 183319-69-9 (HCl) Chemical Formula: C22H24ClN3O4 Exact Mass: Molecular Weight: 429.9 Elemental Analysis: C, 61.47; H, 5.63; Cl, 8.25; N, 9.77; O, 14.89
Related CAS #: 183319-69-9 (HCl) 183321-74-6 (free base)
Synonym: CP-358,774; CP-358774; CP358774; OSI-774; OSI 774; OSI774; Erlotinib hydrochloride; US brand name: Tarceva.
IUPAC/Chemical Name: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride.
InChi Key: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
SMILES Code: COCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC.[H]Cl
Technical Data
Appearance: White to off-white solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Certificate of Analysis: View CoA: previous batch, lot#LC40528 View CoA: previous batch, lot#EOS50121. View CoA: current batch, Lot#CRB70414
QC Data: View QC data: previous batch, lot#LC40528 View QC data: previous batch, lot#EOS50121. View QC data: current batch, Lot#CRB70414
Safety Data Sheet (MSDS): View Material Safety Data Sheet (MSDS)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO at 18 mg/mL with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM.
Shelf Life: >10 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code: 293490
References
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