Metahexamide is an anti-diabetic drug from the group of sulfonylureas. It is long-acting and belongs to the first-generation cyclohexyl-containing sulfonylureas. Price and Availability

Metahexamide is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually 98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote. Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

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2: POLLEN RH, BARNES RH, TANNER DC, STIMSON WH, WILLIAMS RH. Treatment of diabetes with metahexamide. Diabetes. 1960 Jan-Feb;9:25-30. PubMed PMID: 14433864.

3: FORIST AA. Determination of metahexamide in human plasma. Ann N Y Acad Sci. 1959 Sep 25;82:496-501. PubMed PMID: 13823959.

4: MORGENSTERN LL, GARRETT ER. Determination of the half life of metahexamide in normal humans. Ann N Y Acad Sci. 1959 Sep 25;82:502-7. PubMed PMID: 14424136.

5: HABIB SA, KENNAWY MR, HASSANEIN M. Clinical experience with metahexamide in diabetes. J Egypt Med Assoc. 1960;43:14-25. PubMed PMID: 13710259.

6: CONCHA E, JIMENEZ E. [Therapeutic trials with metahexamide in diabetes]. Rev Med Chil. 1960 Dec;88:978-80. Spanish. PubMed PMID: 13694969.

7: WELLER C, MACAULAY A, LINDER M, TRACY JD. Clinical evaluation of metahexamide in the treatment of patients with diabetes mellitus. Metabolism. 1959 Jul 2;8(4 Pt 2):672-5. PubMed PMID: 13666415.

8: HAMWI GJ, SKILLMAN TG, KRUGER FA, ROUSH WH, FREEDY LR. Comparative pharmacology and clinical responses to metahexamide. Ann N Y Acad Sci. 1959 Sep 25;82:547-59. PubMed PMID: 14399399.

9: SUGAR SJ, THOMAS LJ. Clinical studies with metahexamide. Ann N Y Acad Sci. 1959 Sep 25;82:618-23. PubMed PMID: 13835564.

10: HAMWI GJ, SKILLMAN TG, FREEDY LR, ALEXANDER LA. Metabolic studies with metahexamide. Metabolism. 1959 Jul 2;8(4 Pt 2):631-43. PubMed PMID: 13666411.

11: HUSKISSON ID, JACKSON WP. Clinical trial of amino-methylbenzol-sulphonyl-cyclohexylurea (metahexamide) in diabetics after failure of tolbutamide. S Afr Med J. 1960 Jan 9;34:34-5. PubMed PMID: 14405589.

12: MACH B, FIELD RA, TAFT EB. Metahexamide jaundice: report of a case. N Engl J Med. 1959 Aug 27;261:438-40. PubMed PMID: 14419387.

13: FEDER IA, KAHN A. Clinical effectiveness and toxicity of metahexamide in treatment of diabetes mellitus. Metabolism. 1961 Mar;10:246-60. PubMed PMID: 13698510.

14: POLOSA P, MUGHINI L, DI SALVO C, LO TURCO F. [Our experience with the therapeutic use of metahexamide in diabetes mellitus]. Riforma Med. 1960 Nov 26;74:1380-5. Italian. PubMed PMID: 13736904.

15: ANDERSSEN N, SKJAEGGESTAD O. [Thrombocytopenia after treatment with metahexamide and chlorpropamide]. Tidsskr Nor Laegeforen. 1962 Aug 15;82:1037-8. Norwegian. PubMed PMID: 13861324.

16: WEST KM, JOHNSON PC. The comparative pharmacology of tolbutamide, carbutamide, chlorpropamide and metahexamide in man. Metabolism. 1959 Jul 2;8(4 Pt 2):596-605. PubMed PMID: 13666407.

17: OWEN JA Jr. A clinical comparison of tolbutamide, chlorpropamide and metahexamide in the treatment of diabetes. Metabolism. 1959 Jul 2;8(4 Pt 2):667-71. PubMed PMID: 13666414.

18: BAUER HG, SISLER EB, KUNG YT, McGAVACK TH. Some physiologic and therapeutic effects of the hypoglycemic agent, metahexamide, in group of 13 elderly diabetic men. Metabolism. 1959 Jul 2;8(4 Pt 2):644-54. PubMed PMID: 13666412.

19: IZZO JL. Comparison of relative hypoglycemic potencies and metabolic effects of metahexamide, chlorpropamide and tolbutamide in diabetes mellitus. Metabolism. 1959 Jul 2;8(4 Pt 2):621-30. PubMed PMID: 13666410.

20: GARATTINI S, JORI A, PALMA V, TESSARI L. On the hypoglycemizing effect of metahexamide. Experientia. 1959 Oct 15;15:384-5. PubMed PMID: 13826354.

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