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N-Hydroxy-4-((2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)methyl)benzamide hydrochloride

Chemical

C20H21N3O2 . HCl

335.4 . 36.5

1310693-92-5

≥95%

Solid.

Soluble in DMSO.

Manufactured by SynKinase.

Target: HDAC6 | Kinase Group: N/A | Substrate: N/AClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.

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AMBIENT

+4°C

-20°C

Stable for at least 2 years after receipt when stored at -20°C.

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Tubastatin A is a potent and selective HDAC6 inhibitor with an IC₅₀ of 4nM. It has a 100 to 1000-fold selectivity for HDAC6 over other HDAC classes.Product References

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease: C. dYdewalle, et al.; Nat. Med. 17, 968 (2011)

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