Zyagen/MCP-2 Recombinant Protein/7853/1 Ea

作者: 时间:2024-09-20 点击量:

Background

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.5 kDa protein containing 74 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Specifications

Additional Names
Monocyte Chemotactic Protein-2, CCL8, HC14
Preparation
Biological activity was determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0 - 100.0 ng/ml.
Location
GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP
Source
E. coli
Reactivity
n/a
Tested Application
n/a
Storage
The lyophilized MCP-2 recombinant protein is stable for at least 2 years from date of receipt at -20ËšC. Reconstituted MCP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20ËšC. As with any protein, exposing MCP-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Species Reactivity
n/a
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).

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