Note: Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures | |
ProductName | IRS-1(Phospho-Ser639)Antibody |
Synonyms | Insulinreceptorsubstrate-1;IRS-1;IRS1 |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanIRS-1aroundthephosphorylationsiteofSer639. |
ImmunogenRange | 605-654 |
Clonality | Polyclonal |
ApplicationDilutions | IHC:1:50~1:100ELISA:1:20000 |
Specificity | IRS-1(Phospho-Ser639)AntibodydetectsendogenouslevelsofIRS-1onlywhenphosphorylatedatSer639. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | IRS1 |
DatabaseLinks | GeneID: 3667 Swiss-Prot#: P35568 OMIM#: 125853/147545 Unigene#: Hs.471508 |
TargetModification | Phospho |
ModificationSites | H:S639M:S635R:S635 |
ApplicationImages | |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbreastcarcinoma,usingIRS-1(Phospho-Ser639)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |