Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
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Product Name | IRS-1 (Phospho-Ser1101) Antibody |
Synonyms | Insulin receptor substrate-1; IRS-1; IRS1 |
Immunogen | The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser1101. |
Immunogen Range | 1067-1116 |
Clonality | Polyclonal |
Application Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000 |
Specificity | IRS-1 (Phospho-Ser1101) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Ser1101. |
Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability | Stable at -20°C for at least 1 year. |
NCBI Gene Symbol | IRS1 |
Database Links |
Gene ID: 3667 Swiss-Prot #: P35568 OMIM #: 125853/147545 Unigene #: Hs.471508 |
Target Modification | Phospho |
Modification Sites | H:S1101 M:S1097 R:S1100 |
Application Images | |
Image 1 | Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using IRS-1 (Phospho-Ser1101) Antibody. The picture on the right is blocked with the phospho peptide. |
Image 2 | Western blot analysis of lysates from COS7 cells treated with Calyculin A 50ng/ml 30', using IRS-1 (Phospho-Ser1101) Antibody. The lane on the right is blocked with the phospho peptide. |