Antibodies that detect ALS2CR2 can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target ALS2CR2 in Human, Mouse, Rat, Non-human primate and Equine samples. Our ALS2CR2 polyclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. Find the ALS2CR2 antibody that fits your needs. Choose from 1 of 13 ALS2CR2 antibodies, which have been validated in experiments with 34 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you re looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.

Synonyms amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog; CALS-21; ILP-interacting protein; ILP-interacting protein homolog; ILP-interacting protein ILPIPA; MGC102916; polyploidy associated protein kinase; Polyploidy-associated protein kinase; Pseudokinase ALS2CR2; STE20-related kinase adapter protein beta; STRAD beta

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