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商品描述
Description:
Themouseanti-ratIFN-γ monoclonalantibody(cloneDB-2)is,intermsofreactivity,verysimilairtotheDB-1antibody(cat.no.CT032).WhereastheDB-1antibodyisamousemonoclonalantibodyoftheIgG1subtype,cloneDB-2isanIgAsubtype.TheDB-2antibody hasshownnottobindwithrodentIFN-α1 and-β ortohumanIFNs. Theantibody effectivelyneutralizesbothratandmouse IFN-γinvitroandinvivo.(VanderMeideP.H. etal. 1989andIssekutzT.B.etal.1988). Further,theDB-2antibodyisactiveinWesternBlotanalysis (VanderMeideP.H. etal. 1986).
Characteristics:
cloneDB-2Referenceslist:
- TherecruitmentoflymphocytesintotheskinbyTcelllymphokines:theroleofgamma-interferon.Issekutz,TB,etal.Clin.Exp.Immunol.1988Jul;73:70-5
- Isolationandcharacterizationofmonoclonalantibodiesdirectedtoratinterferon-gamma.vanderMeide,PH,etal.LymphokineRes.1989Winter;8:439-49
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