Description:
SMAD transcription factors are the core members of transforming growth factor β (TGF-β) pathway, which has been implicated in the regulation of cell growth, differentiation, apoptosis and specification of developmental fate. The molecular mechanisms of TGF-β/SMAD signaling pathway have been widely studied. The regulatory effect of SMAD complex likely depends on transcriptional modules, in which the SMAD binding elements and partner transcription factor binding sites (SMAD modules) are present in specific context on the promoter regions.>>> 更多资讯详情请访问蚂蚁淘商城