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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
AnthraxProtectiveAntigenAntibodyProperties Description Anti-AnthraxProtectiveAntigen(RABBIT)Antibody-100-401-H55 Host Rabbit KnownCrossReactivity Bacillusanthracis Clonality PolyclonalIgG Application WesternBlot:1:100-1:1000 PhysicalState Liquid ShippingCondition DryIce Format Antiserum Label Unconjugated Concentration 0.5mg/mLbyUVabsorbanceat280nm Buffer 0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2 Preservative 0.05%(w/v)SodiumAzide StABIlizer 0.05%BSA GeneName pagA RelevantLinks UniProtKB-P13423 NCBI-NP_052806.1 GeneID-1158723 |
AnthraxProtectiveAntigenAntibodyDescription
Background
AnthraxPA(ProtectiveAntigen)andAnthraxLF(LethalFactor),alongwithAnthraxEF(EdemaFactor),aretoxinsproducedbyBacillusanthracis.Allthreeoftheproteinsmustbepresentfortoxicentryintocells.AnthraxPAissecretedfromBacillusanthracisasan83kD(PA83)proteinwhichiscleavedbyfurinprotease,releasinga20kDfragment.The63kDportion(PA63)ofthecleavageproductformsaheptamer,whichbindsthetoxinsLFandEF.Thiscomplexentersviareceptor-mediatedendocytosiswhereLFandEFexerttheirtoxiceffects.AnthraxPAisidealforresearchersinterestedinNeuroBIOLOGyresearch.
Synonyms
pag,AnthraxProtectiveAntigen,Anthraxtoxinstranslocatingprotein,PA-83,ProtectiveantigenPA-20,PA20,ProtectiveantigenPA-63,PA63
Immunogen
AnthraxProtectiveAntigenAntibodywasproducedfromwholerabbitserumpreparedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtotheinternalregionoftheAnthraxPAprotein.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AnthraxPA(ProtectiveAntigen)AntibodyissuitbaleforuseinWB.Expectabandapproximately83kDaonspecificlysates.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-AnthraxProtectiveAntigenAntibodyissera.ABLASTanalysiswasusedtosuggestcross-reactivitywithAnti-AnthraxPAfrommultiplespeciesbasedon100%homologywiththeimmunizingsequence.Cross-reactivitywithAnti-AnthraxPAfromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
