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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
AlphaIISpectrinAntibodyProperties Description Anti-AlphaIISpectrin(RABBIT)PolyclonalAntibody-100-401-W92 Host Rabbit TargetSpecies Human KnownCrossReactivity Human,Rat,Mouse Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition WetIce Format IgG Label Unconjugated Buffer None Preservative None StABIlizer None GeneName SPTAN1 RelevantLinks UniProtKB-Q13813 GeneID-6709 NCBI-NP_001123910 |
AlphaIISpectrinAntibodyDescription
Background
Thespectrinfamilyofcytoskeletalproteinsiscomprisedof2alphagenes(a1anda2)andfivebetagenes(ß1-ß5).Spectrinshavebeenshowntofunctionasscaffoldingproteinsinmechanicalsupportoftheplasmamembraneaswellasbindothermembraneproteinsandlipids(BennettandBaines2001).Defectsinspectringeneshavebeenlinkedtosomeformsofhereditaryspherocytosis,atypeofauto-hemolyticanemiawhichischaracterizedbysphericalredbloodcellsthataremorepronetolysis.AlphaIISpectrinAntibodyisidealforresearchersinterestedincellcycleresearch.
Synonyms
Spectrinalphachainnon-erythrocytic1,Fodrinalphachain,Spectrinnonerythroidalphasubunit
Immunogen
Anti-AlphaIISpectrinAntibodywasproducedinrabbitsbyrepeatedimmunizationswitharecombinantcontstructcontainingthe7th,8th,9threpeatsofhumanalphaIIspectrinexpressedinandpurifiedfromE.coli.
ImmunogenType
RecombinantProtein
StorageCondition
Storevialat-20°Cpriortoopeninginundilutedaliquots.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AlphaIISpectrinAntibodyisstoredasaneatserum.ItissuitableforWesternBlotsandImmunofluorescence.Expectabandatapproximately~240kDaonspeificlysatesortissues.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-AlphaIISpectrinAntibodywaspurifiedinaneatserum.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
