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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
14-3-3AntibodyProperties Description Anti-14-3-3(Rabbit)Antibody-612-401-D01 Host Rabbit TargetSpecies Rat KnownCrossReactivity rat Clonality Polyclonal Application WesternBlot:1:1000 PhysicalState Liquid ShippingCondition DryIce Format IgG Label Unconjugated Buffer 0.01MHEPES,0.15MSodiumChloride,pH7.5 StABIlizer 0.1mg/mlBovineSerumAlbumin(BSA)-IgGandProteasefree,50%(v/v)Glycerol GeneName YWHAB RelevantLinks UniProtKB-P35213 GeneID-56011 NCBI-NP_062250.1 |
14-3-3AntibodyDescription
Background
14-3-3Antibodydetects14-3-3protein.14-3-3ismemberofafamilyofhighlyconservedproteinsthatappeartohavemultiplerolesincellsignaling.14-3-3isabundantlyexpressedinthebrainandhavebeendetectedinthecerebrospinalfluidofpatientswithdifferentneurologicaldisorders.14-3-3proteinsbindproteinligandsthataretypicallyphosphorylatedonserineorthreonineresiduesandregulatethefunctionsofthesebindingpartnersbyanumberofdifferentmechanisms.The14-3-3proteinsaffectadiversearrayofcellularprocessesincludingthecellcycleandtranscription,signaltransductionandintracellulartrafficking.Anti-14-3-3antibodyisidealforinvestigatorsinvolvedinCellSignaling,Neuroscience,SignalTransductionresearch.
Synonyms
14-3-3proteinbeta/alpha,PrepronervegrowthfactorRNH-1,ProteinkinaseCinhibitorprotein1
Immunogen
Anti-14-3-3Antibodywasproducedbyrepeatedimmunizationswithsyntheticphospho-peptidecorrespondingtoaminoacidresiduesfromtheC-terminalregion.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Forextendedstorage,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.Diluteonlypriortoimmediateuse.
ApplicationNote
14-3-3antibodyissuitableforuseinWesternBlotting.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandofapproximately29kDainsizecorrespondingto14-3-3proteinintheappropriatecelllysateorextract.
Purity/Specifity
Anti-14-3-3Antibodyisdirectedagainstrat14-3-3protein.Theantibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitypurification.Immunolabelingofthe14-3-3proteinbandiscompletelyblockedbypre-adsorptionoftheantibodywiththepeptidethatwasusedtogeneratetheantibody.Reactivityisexpectedfromthefollowingspeciesbasedon100%sequencehomology:bovine,canine,chicken,human,mouse,non-humanprimates,Xenopusandzebrafish.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
