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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
APC13AntibodyProperties Description Anti-APC13(RABBIT)Antibody-600-401-Y32 Host Rabbit TargetSpecies Human KnownCrossReactivity Human,mouse,rat Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.02%(w/v)SodiumAzide StABIlizer None GeneName ANAPC13 RelevantLinks UniProtKB-Q9BS18 GeneID-25847 NCBI-NP_056206 |
APC13AntibodyDescription
Background
Cellcycleregulatedproteinubiquitinationanddegradationwithinsubcellulardomainsisthoughttobeessentialforthenormalprogressionofmitosis.APC13isahighlyconservedcomponentoftheanaphasepromotingcomplex/cyclosome(APC/C),acellcycle-regulatedE3ubiquitinligasethatcontrolsprogressionthroughmitosisandtheG1phaseofthecellcycle.APC/CisresponsIBLefordegrADInganaphaseinhibitors,mitoticcyclins,andspindle-associatedproteinsensuringthateventsofmitosistakeplaceinpropersequence.TheindividualAPC/CcomponentsmRNAandproteinlevelsareexpressedatapproximatelythesamelevelsinmosttissuesandcelllines,suggestingthattheyperformtheirfunctionsaspartofacomplex.APC13promotesthestableassociationofAPC3/Cdc27andAPC6/Cdc16withtheAPC/C.
Synonyms
APC13Antibody,SWM1,APC13,Anaphase-promotingcomplexsubunit13,Cyclosomesubunit13
Immunogen
Anti-APC13antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha17aminoacidsyntheticpeptideneartheinternalregionofhumanAPC13.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-APC13AntibodyhasbeentestedforuseinELISA,WesternBlottingandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately9kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-APC13Antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithAPC13fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
