Description:

Description:Reninisaproteasethatissynthesizedbythekidneys.RenincatalyzesthehydrolysisofangiotensinogentoangiotensinI,whichisconvertedtoangiotensinII,ahighlypotentvasoconstrictor.Renininhibitorshavebeenusedtherapeuticallyinthetreatmentofhypertension(highbloodpressure).TheReninAssayKitisdesignedtomeasureReninactivityforscreeningandprofilingapplications.Itcomesinaconvenient96-wellformat,withpurified,activatedrenin,reninsubstrate,andassaybufferfor100enzymereactions.AliskirenHydrochlorideisalsoincludedasacontrolforrenininhibition.ThekeytotheReninAssayKitisthespecific,fluorogenicsubstrate.Usingthiskit,onlyonesimplesteponamicrotiterplateisrequiredforreninreactions.Thefluorometricsubstrateisincubatedwithasamplecontainingreninenzymetoproduceafluorophorethatcanthenbemeasuredusingafluorescencereader.Note:Thiskitisalsosuitableforusewithcellextracts.

Format:assaykit

ScientificCategory:Protease/AssayKit

AdditionalInformation:

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Name	ReninAssayKit
RelatedProductNames	ReninAssayKit
Format	AssayKit
Storage	Mixedstorage
IntendedUse	ResearchUseOnly