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Product |
PDE4A11 Antibody Affinity Purified |
Description | Affinity Purified Phosphodiesterase 4A11 Antibody N-epitope |
Verified Applications | ELISA, IMM, WB |
Host | Rabbit |
Species Cross Reactivity | Human |
Immunogen | Synthetic peptide taken within amino acid region 50-100 on human PDE4A11 protein. |
Accession # | GenBank: AAU82096 |
Physical Properties | |
Quantity |
100 µg |
Volume | 200 µl |
Concentration | 0.45-0.65 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | N-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
DB | 1:10,000 |
ELISA | 1:10,000 |
Immunoprecipitation | 1:150 |
Western Blot | 1:500 |
Protein | |
Uniprot # |
P27815 |
Overview | Hydrolyzes the second messenger cAMP which is a key regulator of many important physiological processes. |
Molecular Function | cAMP |
Subcellular Location | Isoform 1: perinuclear region, Isoform 2: ruffle membrane, Isoform 4: Peripheral membrane protein, Isoform 6: perinuclear region, Isoform 7: Membrane, Cytoplasm |
Expression | Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Iso |
Structure | Belongs to cyclic nucleotide phosphodiesterase family. PDE4 subfamily |
Alternative Nomenclature | 5-cyclic phosphodiesterase 4A11 antibodyPDE46 antibodyphosphodiesterase 4A11 cAMP specific antibody phosphodiesterase isozyme 4A11 antibodyphosphodiesterase type 4A11 antibody |
Protein information supplied by UniProt
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