Product | Galectin 3 AntibodyN-epitope |
Verified Applications | ELISA, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Mouse, Rat |
Immunogen | N-epitope synthetic peptide taken within amino acid sequences 1-100 on human Galectin 3 protein. |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.55-0.75 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | N-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
DB | 1:10,000 |
ELISA | 1:10,000 |
| Immunoprecipitation | 1:200 |
Western Blot | 1:500 |
Protein | |
Uniprot # | P17931 |
Overview | Galactose-specific lectin which binds IgE. Mediates the alpha-3, beta-1 integrin the stimulation CSPG4 of endothelial cells migration. Invovled in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. |
Molecular Function | IgE-binding protein, Lectin |
Subcellular Location | Cytoplasm; Nucleus; Secreted |
Expression | Found in colonic epithelium. Abundant in activated macrophages. Expressed in fetal membranes. |
Structure | Probably forms homodimer or heterodimers. Forms complex with the ITGA3, ITGB1 and CSPG4. |
Alternative Nomenclature | 35 kDa lectin antibody Carbohydrate-binding protein 35 antibody CBP 35 antibody GAL3 antibody Galactose specific lectin 3 antibody Galactoside-binding protein antibody GALBP antibody GALIG antibody GBP antibody IgE binding protein antibody L 31 antibody L 34 antibody Laminin-binding protein antibody Lectin galactose binding soluble 3 antibody Lectin L-29 antibody Lectin, galactose binding, soluble 3 antibody LGALS 3 antibody LGALS2 antibody MAC 2 antigen antibody Macrophage galactose-specific lectin antibody |
Protein information supplied by UniProt
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