Product | PDE1A Antibody |
Description | Affinity Purified Phosphodiesterase 1A Antibody C-epitope |
Verified Applications | CM, ELISA, ICC, IF, IHC, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide taken within amino acid region 51-101 on human PDE1A protein. |
| Specificity | This antibody will not label other PDE family members. This antibody will label all PDE1 variants including PDE1A1, PDE1A3, PDE1A5. |
Accession # | NCBI: NP001009978.1 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.6 µg/µl in antibody stabilization buffer |
Immunoglobulin | IgG |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | C-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
ELISA | 1:10,000 |
Immunocytochemistry | 1:200 |
Immunofluorescence | 1:200 |
Immunohistochemistry | 1:200 |
Immunoprecipitation | 1:200 |
Western Blot | 1:500-1:1,000 |
Protein | |
Uniprot # | Q9JLL9 |
Overview | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP. |
Molecular Function | Hydrolase, calcium- and calmodulin-regulated 3,5-cyclic-GMP phosphodiesterase activity, metal ion binding |
Subcellular Location | Cytosol |
Expression | Several tissues, including brain, kidney, testes and heart. |
Structure | Belongs to thecyclic nucleotide phosphodiesterase family.PDE1 subfamily. |
Alternative Nomenclature | 3 5 cyclic nucleotide phosphodiesterase antibody 61 kDa Cam PDE antibody Calcium/calmodulin dependent 3 5 cyclic nucleotide phosphodiesterase 1A antibody Calcium/calmodulin-dependent 3 antibodyCalmodulin-dependent Phosphodiesterase antibodyCam PDE 1A antibody HSPDE1A antibodyMGC26303 antibody PDE1A antibody Phosphodiesterase 1A antibodyPhosphodiesterase 1A calmodulin dependent antibody |
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