Product | PDE4B Antibody |
Description | Affinity Purified cAMP-specific 3,5-cyclic phosphodiesterase 4B Antibody N-epitope |
Verified Applications | CM, ELISA, ICC, IF, IHC, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide common to all PDE4B subtypes taken near N-terminal |
| Specificity | This antibody detects all PDE4B proteins, including PDE4B1, PDE4B2, PDE4B3, and a 66 kDa PDE4B variant. It does not cross-react with other PDE family members such as PDE4A, PDE4C. PD4B-201AP may have minor crossreactivity to PDE4D. Antibody PD4B-212AP does not have any cross reactivity with any other PDE family members other than: PDE4B1, PDE4B2, PDE4B3, PDE4B4. |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.68 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | N-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
Confocal Microscopy | 1:250 |
DB | 1:10,000 |
ELISA | 1:10,000 |
Immunocytochemistry | 1:250 |
Immunofluorescence | 1:250 |
Immunohistochemistry | 1:250 |
Immunoprecipitation | 1:350 |
Western Blot | 1:500-1:1,000 |
Protein | |
Uniprot # | Q07343 |
Overview | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
Molecular Function | Hydrolase, 3,5-cyclic-AMP phosphodiesterase activity, cAMP binding |
Expression | Expressed in brain, heart, lung and skeletal muscle. |
Alternative Nomenclature | 5-cyclic phosphodiesterase 4B antibody cAMP-specific 3 antibody cAMP-specific 3,5-cyclic phosphodiesterase 4B antibody DPDE4 antibody dunce-like phosphodiesterase E4 antibody MGC126529 antibody PDE 4B antibody PDE IVB antibody PDE32 antibody PDE4B5 antibody PDEIVB antibody Phosphodiesterase 4B antibody Phosphodiesterase-4B cAMP-specific (dunce (Drosophila)-homolog) antibody |
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