Product | PDE2A1 Antibody |
Description | Affinity Purified Phosphodiesterase 2A1 Antibody N-epitope |
Verified Applications | ELISA, IHC,IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Monkey, Mouse, Rat |
Immunogen | Synthetic peptide corresponding to region within amino acids 1-50 on N-terminus of human PDE2A1 protein. |
| Specificity | This antibody will detect PDE2A1 only. |
Accession # | NCBI: NP_001230713.1 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin | IgG |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | N-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
ELISA | 1:10,000 |
| Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot | 1:500 |
Protein | |
Uniprot # | O00408 |
Overview | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration. |
Molecular Function | Calcium channel activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; drug binding; metal ion binding; protein homodimerization activity; TPR domain binding. |
Subcellular Location | Cytoplasm |
Expression | Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas. |
Structure | Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily. Contains 2 GAF domains. |
Alternative Nomenclature | Phosphodiesterase 2A 1 |
>>> 更多资讯详情请访问蚂蚁淘商城
