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FabGennix/PDE1C Antibody/PD1C-301AP/

作者: 时间:2024-09-20 点击量:

General Information

Product

PDE1C Antibody

Description

Affinity Purified Human 3,5 cyclic nucleotide phosphodiesterase (HSPDE1C1A)Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.

SpecificityThis antibody does not cross-react with PDE1A, PDE1B, or other PDE family members. This antibody will label all PDE1C variants including PDE1C1, PDE1C2, and PDE1C3.

Accession #

GenBank: U40371.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20C for long term storage

Application Protocol

Confocal Microscopy

1:40-1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:40-1:100

Immunofluorescence

1:100

Immunohistochemistry

1:40-1:100

Immunoprecipitation

1:200

Western Blot

1:500-1:2,000

Protein

Uniprot #

Q14123

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.

Molecular Function

Hydrolase, calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, metal ion binding

Subcellular Location

Cytosol

Expression

Expressed in several tissues, including brain and heart.

Structure

Homodimer

Alternative Nomenclature

5-cyclic nucleotide phosphodiesterase 1C

Calcium/calmodulin dependent 35 cyclic nucleotide phosphodiesterase 1C

Cam PDE 1C

HCAM3

HSPDE1C1A

Human 35 cyclic nucleotide Phosphodiesterase

PDE 1C

Phosphodiesterase 1C

Phosphodiesterase 1C calmodulin dependent

Protein information supplied by UniProt

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